Ontario Provincial Police (OPP) says multiple injuries have been reported following a crash involving several vehicles on the westbound portion of Highway 401 near Guelph.
Officers with Mississauga OPP were notified of a serious crash just west of Highway 6.
Two vehicles were involved, including a transport truck and a car. One driver was transported to a trauma centre with serious injuries. OPP said westbound lanes are closed, and traffic is exiting at Highway 6 north.
OPP responded to another collision on the highway involving two commercial vehicles and a passenger van. One driver was transported to a trauma centre via Ornge air helicopter, and another driver was rushed to a trauma centre via ambulance.
All westbound lanes will be closed at Guelph Line for the investigation.